In many cases there are not enough reference weights available for calibrations of non-automatic electronic weighing instruments. Moreover, placing the reference weights on the weighing instrument may prove to be difficult if the load receptor lacks sufficient space. Therefore, the substitution procedure is an appropriate option for calibrating high-capacity scales. The guideline contains additional requirements regarding the practical implementation of the substitution procedure, thus supporting the high competence required of an accredited calibration laboratory. The process of the substitution procedure is clearly illustrated by means of a specific example. The guideline helps to standardise the substitution procedure in the calibration of non-automatic weighing instruments. It should be noted that the measurement uncertainty during calibration and during use is significantly increased by the substitution procedure. The requirements regarding the use of the substitution procedure aim to ensure the practicality and comparability of the calculation of the uncertainty of measurement during calibration and when using the weighing instrument. The guideline is based on the calibration guideline DKD-R 7-2, Edition 01/2018 translation of the EURAMET Calibration Guide No.18 Version 4.0 (11/2015)].